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Table representation of search results timeline featuring number of search results per year.

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The following term was not found in PubMed: III001420
Page 1
Protein-coding tRNA sequences?
Jimenez J. Jimenez J. Gene. 2022 Mar 10;814:146154. doi: 10.1016/j.gene.2021.146154. Epub 2022 Jan 4. Gene. 2022. PMID: 34995735
Transfer RNAs (tRNAs) are ancient molecules likely predating the translation machinery. These extremely conserved RNA molecules transfer amino acids to the ribosome for the synthesis of proteins encoded by mRNAs, but canonical tRNAs are not protein-coding RNA …
Transfer RNAs (tRNAs) are ancient molecules likely predating the translation machinery. These extremely conserved RNA molecules trans …
The conserved hypothetical protein Tb427.10.13790 is required for cytokinesis in Trypanosoma brucei.
Mudogo CN, Werner SF, Mogk S, Betzel C, Duszenko M. Mudogo CN, et al. Acta Trop. 2018 Dec;188:34-40. doi: 10.1016/j.actatropica.2018.08.029. Epub 2018 Aug 25. Acta Trop. 2018. PMID: 30153427
HAT therapy relies upon drugs which use is limited by toxicity and rigorous treatment regimes, while development of vaccines remains elusive, due to the effectiveness of the parasites antigenic variation. Here, we evaluate a hypothetical protein Tb427.10.13790, as a …
HAT therapy relies upon drugs which use is limited by toxicity and rigorous treatment regimes, while development of vaccines remains elusive …
Molecular characterization and protective efficacy of a new conserved hypothetical protein of Eimeria tenella.
Zhao H, Zhu S, Zhao Q, Huang B, Liu G, Li Z, Wang L, Dong H, Han H. Zhao H, et al. Parasite. 2021;28:40. doi: 10.1051/parasite/2021037. Epub 2021 May 3. Parasite. 2021. PMID: 33944773 Free PMC article.
However, more than 70% of the gene models for this species are currently annotated as hypothetical proteins. In this study, a conserved hypothetical protein gene of E. tenella, designated EtCHP18905, was cloned and identified, and its immune pro …
However, more than 70% of the gene models for this species are currently annotated as hypothetical proteins. In this study, a …
Functional and structural characterization of Hyp730, a highly conserved and dormancy-specific hypothetical membrane protein.
Fannin S, Rangel J, Bodurin AP, Yu T, Mistretta B, Mali S, Gunaratne P, Bark SJ, Ebalunode JO, Khan A, Widger WR, Sen M. Fannin S, et al. Microbiologyopen. 2021 Jan;10(1):e1154. doi: 10.1002/mbo3.1154. Microbiologyopen. 2021. PMID: 33650800 Free PMC article.
A pertinent example is Mycobacterium tuberculosis (H37Rv), which contains ~4000 protein-coding genes, with almost a thousand having been categorized as 'membrane protein', and a few of which (~1%) have been functionally characterized and structurally modeled. ...Our …
A pertinent example is Mycobacterium tuberculosis (H37Rv), which contains ~4000 protein-coding genes, with almost a thousand having b …
An ELISA immunoassay employing a conserved Leishmania hypothetical protein for the serodiagnosis of visceral and tegumentary leishmaniasis in dogs and humans.
Carvalho AMRS, Costa LE, Salles BCS, Santos TTO, Ramos FF, Lima MP, Chávez-Fumagalli MA, Silvestre BT, Portela ÁSB, Roatt BM, Silveira JAG, Gonçalves DU, Magalhães-Soares DF, Duarte MC, Menezes-Souza D, Coelho EAF. Carvalho AMRS, et al. Cell Immunol. 2017 Aug;318:42-48. doi: 10.1016/j.cellimm.2017.06.001. Epub 2017 Jun 8. Cell Immunol. 2017. PMID: 28602279
In the present study, a conserved Leishmania hypothetical protein, namely LiHypA, was evaluated for the serodiagnosis of visceral and tegumentary leishmaniasis in dogs and humans. This protein showed a high amino acid sequence homology between viscerot …
In the present study, a conserved Leishmania hypothetical protein, namely LiHypA, was evaluated for the serodiagnosis o …
The conserved hypothetical protein PSPTO_3957 is essential for virulence in the plant pathogen Pseudomonas syringae pv. tomato DC3000.
D'Amico K, Filiatrault MJ. D'Amico K, et al. FEMS Microbiol Lett. 2017 Apr 1;364(8). doi: 10.1093/femsle/fnx004. FEMS Microbiol Lett. 2017. PMID: 28073812
There are a substantial number of genes in sequenced bacterial genomes, including P. syringae, that encode for conserved hypothetical proteins; some of these have been functionally characterized in other Pseudomonads and have been demonstrated to play importa …
There are a substantial number of genes in sequenced bacterial genomes, including P. syringae, that encode for conserved hypotheti …
Identification of a novel, small, conserved hypothetical protein involved in Brucella abortus virulence by modifying the expression of multiple genes.
Tian M, Lian Z, Bao Y, Bao S, Yin Y, Li P, Ding C, Wang S, Li T, Qi J, Wang X, Yu S. Tian M, et al. Transbound Emerg Dis. 2019 Jan;66(1):349-362. doi: 10.1111/tbed.13028. Epub 2018 Oct 16. Transbound Emerg Dis. 2019. PMID: 30267618
In this study, we identified a novel gene bab_RS22045 that encodes a small highly conserved protein in Rhizobiales. To investigate the role of this gene, a deletion mutant and complement strain were constructed. ...Additionally, heterogeneous complementary analysis …
In this study, we identified a novel gene bab_RS22045 that encodes a small highly conserved protein in Rhizobiales. To investi …
Identification of a Highly Conserved Hypothetical Protein TON_0340 as a Probable Manganese-Dependent Phosphatase.
Sohn YS, Lee SG, Lee KH, Ku B, Shin HC, Cha SS, Kim YG, Lee HS, Kang SG, Oh BH. Sohn YS, et al. PLoS One. 2016 Dec 1;11(12):e0167549. doi: 10.1371/journal.pone.0167549. eCollection 2016. PLoS One. 2016. PMID: 27907125 Free PMC article.
A hypothetical protein TON_0340 of a Thermococcus species is a protein conserved in a variety of organisms including human. ...Mg2+ binds to TON_0340 less tightly and activates the phosphatase activity less efficiently than Mn2+. Whereas Ca2+ and Zn2+ …
A hypothetical protein TON_0340 of a Thermococcus species is a protein conserved in a variety of organisms inclu …
Conserved hypothetical protein Rv1977 in Mycobacterium tuberculosis strains contains sequence polymorphisms and might be involved in ongoing immune evasion.
Jiang Y, Liu H, Wang X, Li G, Qiu Y, Dou X, Wan K. Jiang Y, et al. Int J Clin Exp Pathol. 2015 Jun 1;8(6):6891-900. eCollection 2015. Int J Clin Exp Pathol. 2015. PMID: 26261576 Free PMC article.
Here, we selected 151 clinical Mycobacterium tuberculosis isolates from China, amplified gene encoding Rv1977 and compared the sequences. The results showed that Rv1977, a conserved hypothetical protein, is not conserved in M. tuberculosis strains and …
Here, we selected 151 clinical Mycobacterium tuberculosis isolates from China, amplified gene encoding Rv1977 and compared the sequences. Th …
Neisseria conserved protein DMP19 is a DNA mimic protein that prevents DNA binding to a hypothetical nitrogen-response transcription factor.
Wang HC, Ko TP, Wu ML, Ku SC, Wu HJ, Wang AH. Wang HC, et al. Nucleic Acids Res. 2012 Jul;40(12):5718-30. doi: 10.1093/nar/gks177. Epub 2012 Feb 28. Nucleic Acids Res. 2012. PMID: 22373915 Free PMC article.
We show here that the Neisseria conserved hypothetical protein DMP19 acts as a DNA mimic. The crystal structure of DMP19 shows a dsDNA-like negative charge distribution on the surface, suggesting that this protein should be added to the short list of k …
We show here that the Neisseria conserved hypothetical protein DMP19 acts as a DNA mimic. The crystal structure of DMP1 …
1,641 results